Should be used with caution among athletes.

[Drug name]

Generic Name: Gestrinone 2.5 mg Capsules

English name/Latin name: Gestrinone 2.5 mg Capsules

[Composition]

The main ingredient of this product is Gestrinone. Chemical name: D-18 methyl-17 α-ethynyl-17 β-hydroxy-4, 9, 11-estratrien-3-one.

[Description] The content of this product is light yellow powder.

[Indications] It is used for endometriosis.

[Posology and Method of Administration]

Oral: for endometriosis, generally 2.5 mg (1 capsule) each time, twice a week, the first time on the first day of menstruation, the second time 3 days later, and the same time every week thereafter; If a dose is missed, a dose of 2.5 mg (1 capsule) should be taken immediately, and the dose should be continued on schedule (for example, if a patient who takes a dose on Monday and Thursday misses a dose on Monday, she can take the missed dose on Tuesday or Wednesday, continue to take the dose on Thursday and then continue to take the dose on Monday and Thursday); For a patient who misses multiple doses, the drug should be suspended until she restarts to take the dose on the first day of the next menstrual cycle. The course of treatment of this product is 6 months.

[Pharmacological effects] This product is a synthetic triene 19 norsteroid compound with complex hormonal and anti-hormonal properties. It not only has strong anti-progestational and anti-estrogenic activities, but also has weak estrogenic and androgenic effects. Animal experiments have shown that it can inhibit the secretion of progesterone, but also has the effect of progesterone on endometrium, causing the inactivation and degeneration of endometrium and ectopic focus cells, resulting in atrophy of ectopic focus. Its anti-fertility effects may be due to inhibiting ovulation and endometrial development, changing the nature of cervical mucus, affecting the speed of ovum movement and antagonizing endometrial progesterone receptor, thus interfering with ovum implantation.

[Storage] Preserve in tightly-closed containers, protected from light.

[Packaging] Aluminum-plastic package, 8 capsules per sheet, 1 sheet per pack.

Aluminium-plastic packaging, 10 capsules per sheet, 1 sheet per pack.

[Shelf Life] 24 months