Generic name: Levonorgestrel and Quinestrol Tablets

Trade name: Lebostrol

English name: Levonorgestrel and Quinestrol Tablets

[Ingredients] This product is a compound preparation, each tablet contains 6mg levonorgestrel and 3mg quinestrol.

[Description] Film-coated tablets, with white or off-white core.

[Indications] This product can inhibit ovulation and is a long-acting oral contraceptive for women.

[Posology and Method of Administration]

1. From the day of menstruation, take one tablet after lunch on the 5th day, and take the second tablet at an interval of 20 days, or take one tablet each on the 5th day and the 10th day of menstruation. Thereafter, take one tablet per month according to the day of the second dose as the medication day of each month. Withdrawal bleeding usually occurs 6 to 12 days after the drug is taken.

2. When switching from short-acting oral contraceptives to long-acting contraceptives, one tablet of long-acting contraceptives can be taken on the second day after taking 22 tablets, and one tablet of long-acting contraceptives should be taken every month on the same date as starting to take long-acting contraceptives.

[Pharmacological Effect]

Quinylestradiol (ethinylestradiol cyclopentyl ether) is a long-acting estrogen, which is absorbed through gastrointestinal tract after oral administration, stored in adipose tissue, and slowly releases ethinylestradiol. It inhibits ovarian ovulation by inhibiting the hypothalamus-pituitary-ovary axis, so as to achieve long-acting contraceptive effect. When progesterone is compatible with it, it not only has synergistic effect on inhibiting ovulation, but also makes the endometrium transform, presenting secretion phenomenon, leading to withdrawal bleeding and forming periodic changes. When the medicine is taken once a month, the contraceptive rate can reach over 98%.

[Storage] Preserve in tightly-closed containers, protected from light.

[Packaging] Aluminum plastic package, 6 tablets/sheet/pack, 5 tablets/sheet/pack

[Shelf Life] 60 months